LCFA/BMS/ILCF Disparities in Clinical Oncology Research Grants in Translational Immuno-oncology
Funding Opportunity Description
Lung Cancer Foundation of America (“LCFA”) and the International Lung Cancer Foundation (“ILCF”), with financial support from Bristol-Myers Squibb (“BMS”), seek applications for the LCFA/BMS/ILCF Disparities in Clinical Oncology Research Grants in Translational Immuno-oncology.
LCFA, BMS, and ILCF are committed to advancing innovative lung cancer research with a focus on immunotherapy leading to transformative treatment protocols. However, we recognize that not all Young Investigators are represented by the traditional comprehensive cancer research centers which typically make up the NCI pipeline of funding. With these Disparities in Clinical Oncology Research Grants, we aim to fund Young Investigators from under-represented populations and under-funded institutions.
The objective of the LCFA/BMS/ILCF Disparities in Clinical Oncology Research Grants (“Grants”) is to support research in translational immuno-oncology, undertaken by early-career investigators from under-represented populations and under-funded institutions, that aims to improve the care and treatment of individuals with lung cancers.
Examples, though not exclusive, include studies that focus on:
Research Focus and Overview
Successful applications submitted for this RFA require a research approach that seeks to make an immediate and relevant impact through immuno-oncology on lung cancer patient care or interpret the results of a clinical trial from a molecular basis as appropriate to help inform decisions in future clinical trials.
ELIGIBILITY: Education and Experience
At the time of application, eligible applicants must meet these criteria:
NOTE: Exceptions to the seven-year criterion (but not academic rank) can be made for those who may have had interruptions in their career. To request an exemption, contact the ILCF (firstname.lastname@example.org) prior to submission of the application.
The applicant may not currently be or previously have been:
The foregoing notwithstanding, the following candidates may be eligible:
Grant Structure and Allocation
The Grant will be $100,000 per year for up to each of two years. The second year of support is based on the Grantee demonstrating satisfactory research progress as determined by LCFA/ILCF as well as the availability of funding from LCFA/ILCF.
No more than 50% of the requested budget for the Grant may be used for a Grantee’s salary and/or fringe benefits. Grant budget may not be used to fund the purchase of permanent equipment. No indirect costs are provided. Any unused Grant funds at the conclusion of the study period will be returned to LCFA.
|How to Apply||
Applications will be accepted through the International Lung Cancer Foundation’s online application portal only. To access the application:
After initiating an application, you may return to the portal as needed to continue work on tyour application until it is submitted. Applications that have been submitted are no longer editable.
Factors Considered in Evaluating Applications
Projects must be feasible, have strong scientific merit, innovative and relevant to the missions of LCFA and ILCF. The applications will be reviewed by an IASLC Review Committee and the LCFA Scientific Advisory Board in accordance with their current agreed-upon review process. The Application should be structured to provide the following:
Note: LCFA/ILCF is not likely to fund studies undertaken entirely in murine models or cell line xenografts (must use patient biospecimens or PDX’s from local patients).
Peer Review Results of Full Applications
In the first round of review, applications will be reviewed and scored by a sub-committee of the IASLC’s Career Development and Fellowship Committee. Applications are scored using a nine-point rating scale, adapted from the NIH grant scoring rubric.
Based on the scoring from the first round, the finalists will be evaluated by LCFA’s Scientific Advisory Board, who will make the final selections.
Applicants will be informed of the outcome of the peer review process by December 15, 2022 for Grant funding to start on or around April 1, 2023.
TERMS AND CONDITIONS
The following Terms and Conditions apply to the LCFA/BMS/ILCF Grant application process and the Grant which Terms and Conditions must be confirmed and affirmed fully by the Grantee and his/her institution no later than the commencement date of the Grant Term.
Tobacco Funded Research
LCFA/ILCF will not provide research opportunities or other funding to investigators who have received funding from the tobacco industry or their agencies.
Applicant’s institution must agree to approximately 50% of full-time professional effort for the applicant to dedicate to research.
Authorized Grant Holders
LCFA/ILC Foundation Research Grants go to individuals only and not institutions. No Grant may be held by or transferred to another individual.
Change of Budget
Requests for changes in budget require prior approval by LCFA/ILCF. All requests must be in writing. When requesting a change in budget, the Grantee must indicate: the amount, from what budget-line and to what budget-line the monies are being transferred. In the case of supply or equipment budget, all items must be itemized.
The LCFA/ILCF Grant requires that studies funded involve samples from human subjects with whom the investigator has direct personal contact (the “handshake rule”)
Whenever human subjects are a part of a LCFA/ILCF research funded project, the following documents must be received by LCFA/ILCF no later than the time of Grant notification:
- A copy of the Institutional Review Board (IRB) approval and approved patient consent forms. LCFA/ILCF encourages applicants to submit their projects to the appropriate human subjects IRB at the time of application.
- Research involving human adult stem cells or use of human fetal tissue requires one copy of the appropriate institutional committee approval.
- IRB approval and approved patient consent forms must be provided to LCFA/ILCF no later than the time of grant notification. There will be exceptions.
The parties to this RFA shall each assume sole responsibility for its actions regarding any and all claims, losses, and liability arising out of the breach of any of its obligations in this RFA. In no event shall either party to the RFA be liable for any lost profits, lost savings, consequential, incidental, or special damages, or attorneys’ fees, even if such party has been advised of the possibility of such damages.
First Year Progress Report
An annual progress report must be received within 30 days after the end of the first year of the Grant Term. This report must include a financial disbursement report as well as a full report on the progress made in the first year of the Grant. The reports must be submitted via ILCF’s online portal where they will be reviewed by members of LCFA’s Scientific Advisory Board (SAB). Within 30 days of report submission, the SAB will evaluate whether the progress made in the first year is deemed satisfactory, and if so, the second year of funding will be approved, and the quarterly grant payments will continue.
A final report must be received within 90 days after the conclusion of the second year of the Grant. The report must be submitted via ILCF’s online portal and will be reviewed by members of the LCFA’s Scientific Advisory Board and members of the ILCF Board of Directors. The final report will include details of the research outcomes and next steps as well as the final financial disbursement report.
A complete financial disbursement report must be received by LCFA/ILCF within 45 days after the close of the first year of the Grant Term before consideration will be given for the renewal of the Grant for the second year.
At the conclusion of the Grant Term, the Grantee shall submit a complete financial disbursement report covering the entire Grant Term to LCFA/ILCF. LCFA/ILCF. The disbursement report must account for all Grant expenditures during the Grant Term as approved by LCFA/ILCF. Any Grant funds found to have been used for unauthorized expenditures or any unexpended Grant funds, must be returned to LCFA/ILCF, with the disbursement report, within 45 days after the Grant has terminated.
The results of all funded research must be open and shared. All publications and/or presentations at scientific conferences, meetings, and media interviews based on research conducted from this Grant must include a citation as follows: “With Grant Support from Lung Cancer Foundation of America and International Lung Cancer Foundation.” Reprints of abstracts, manuscripts, or other articles that reflect research done after Grant acceptance must be submitted to LCFA/ILCF.
A copy of all publications, presentations, abstracts and the like that report research supported by LCFA funds must be submitted to LCFA's Board of Directors and Scientific Review Board at the time of publication. This information will be included as part of the Grantee’s file and will help LCFA educate patients, caregivers, donors and others about the progress of the proposed research.
Renewal of the LCFA/ILC Foundation Grant is based on a demonstration of satisfactory progress and availability of funding and is at the discretion of LCFA and ILCF. Grantees are required to complete a LCFA/ILCF Renewal Application form for each year the Grant is subject to renewal.
The maximum amount of funds expendable for travel is $1,000 per year.
Relationship of Parties
Grants are made to the institutions to support the Grantee and the project set forth in the Grantee’s application. It is understood by all parties to this RFA that this Grant in no way constitutes an employer-employee relationship between the LCFA/ILCF and the Grantee or the Grantee’s institution.
LCFA and ILCF will determine the way they will publicize the Grant and the Grantee, subject to the approval of both parties. Standard publicity could include recognition in organization publications, press releases, social media and inclusion in other announcements to the organizations' members and constituents.
Upon termination of a Grant prior to the end of the Grant Term for any reason and regardless of by whom, LCFA/ILCF must be notified immediately. A final report of expenditures must be submitted within thirty days of the termination together with the refund of any unexpended balance of the Grant proceeds. A final progress report must be submitted at this time including a completed intellectual property form.
LCFA and ILCF request that the Grantee provide any change of address or position or name of Grantee, together with changes in executive or fiscal officers of the institution to maintain an up-to-date database.
Modification to the Grant
Should the Grantee wish to discontinue the project, leave the designated institution, take a leave of absence for any reason, or modify any part of the Grant, the Grantee must seek approval from the LCFA and ILCF in advance. Failure to comply with this requirement may result in immediate termination of the Grant and may jeopardize any future Grants to the institution by the LCFA and ILCF.
LCFA’s mission is the dramatic improvement in survivorship of lung cancer patients through the funding of transformative science, with the ultimate goal of curing lung cancer. To accomplish this, LCFA works to raise funds for lung cancer research as well as the national profile of lung cancer in order to substantially increase the support of innovative and groundbreaking research efforts.
The International Lung Cancer Foundation (ILCF) aims to accelerate the pace of thoracic malignancy research, to inspire researchers to focus their careers on lung cancer, and to reduce the worldwide lung cancer mortality rate. Established in 2014, the ILCF has provided over $5 million towards global lung cancer research. Through the power of collaboration, support from Pharma, and generous individual donors, the ILCF inspires hope through research.
With these new grants, LCFA and ILCF will have partnered to grant more than $5 million in innovative and groundbreaking lung cancer research grants.
Any questions about this RFA may be directed to email@example.com